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Job Reference: MR234

NGS Scientist

  • Monmouth JunctionNew Jersey
  • £56300 - £91400 per annum
  • Permanent / Full Time

Seven Life Science have an amazing opportunity available as a NGS Scientist, this role is based in Monmouth JCT, New Jersey, U.S.

About The Organization

  • Acutis is a specialized medical laboratory that complements its hard science with the soft skills of its support teams.
  • This combination allows practitioners to diagnose and treat with greater confidence and with ease
  • Acutis serves the medical community and related fields by providing rapid, reliable diagnostic insights that impact clinical decisions in: infectious disease, clinical toxicology for substance use testing and medication monitoring and oncology
  • We are a biomedical specialty laboratory that has no tolerance for error.
  • A company as thorough as it is principled: dedication to the advancement of medical testing, industry-leading turnaround time, and world-class service
  • Every sample we take and every report we relay is prepared with this end in mind: to provide our customers with the highest level of certainty possible.
  • With a service-first mindset, specialized laboratory capabilities, and the agility to adapt as next-generation therapies evolve, Acutis stands at the Service of Science
  • Additionally, building on our platform of advanced science and technology, we have introduced to healthcare professionals to Acutis Reveal™, molecular tests for infectious diseases
  • These new tests offer physicians and clinicians a greater degree of certainty than any standard or traditional test can
  • These new products offer further evidence of Acutis’ passion for innovative technologies and strategies
  • Acutis conducts pioneering research for diagnostic services.
  • We employ NGS, targeted PCR, LC-MS/MS, enhanced microbiology techniques and algorithm-based software to develop new diagnostic solutions.


  • Acutis, a leader in clinical laboratory industry, is building oncology molecular testing with a focus on next generation sequencing (NGS) for clinical trials as well as standard of care
  • At this stage Acutis is looking for highly skilled NGS professionals at Principal Scientist, Senior Scientist or Associate Director level in the NJ location.


  • Following the directions from the NGS Head and management, develop, validate, qualify, and implement NGS tests for tumor FFPE tissues and cell-free DNA (cfDNA); somatic as well as germline gene alterations.
  • Function as a SME for analytical method issues and perform the bench works
  • Lead and participate in tech transfer of analytical methods.
  • Contribute to method validation plan, and drafting testing protocol and standard operating procedure (SOP)
  • Evaluate and implement applicable reference materials and assay QC parameters applicable to NGS, and apply the right assay orthogonal testing, e.g. PCR, ddPCR to verify a NGS assay
  • Coordinate with Bioinformatics group, internally and externally, to process sequence data into reportable genetic calls
  • Contribute to and draft assay validation reports, and prepare scientific presentations and deliver them to project teams and management
  • Following assay validation, perform clinical sample testing.
  • Align with department and corporate goals.
  • Review and approve protocol/procedure deviation investigations, and work with QA representative to establish corrective action/preventive action (CAPA) plan
  • Independently interpret data from performed experiments and consult with the NGS lead and management as needed
  • Maintain excellent documentation of experiments and studies
  • Troubleshoot and optimize assay performance in conjunction with the manager and peers.
  • Report on project progress and present data effectively at team and management meetings
  • Assist with lab organization and compliance with lab safety protocols
  • Comply with the federal and local lab regulatory requirements including but not limited to CLIA, and follow applicable rules and guidelines.

Position Requirements

Required Education and Experience

  • Ph.D. in Cell and/or Molecular Biology, Biophysics, Biochemistry, or a related discipline
  • 3+ years of hands-on experience in NGS at a clinical lab, pharmaceutical company and/or academic institution
  • Master’s degree with 7+ years of experience can be acceptable.
  • Experience in NGS method development on Illumina TSO500 (preferred) or any other Illumina platforms, including library construction, sequencing, BI interpretation and reporting.
  • Good experience in nucleic acid extraction from tissues as well as plasma, manually and via automated extraction
  • Deep understanding of molecular biology and biochemical techniques relevant to assay development
  • Strong analytical and troubleshooting skills.
  • Excellent verbal and written communication skills and willingness to collaborate cross-functionally in a fast-paced and dynamic environment
  • Self-motivated, focused, organized, and thorough with attention to details
  • Demonstrate independent reasoning and problem-solving and troubleshooting skills
  • Efficient utilization of Microsoft PowerPoint, Excel, Word and Outlook

Working with Seven Life Science:

We have been helping professionals find exciting new roles for almost a decade, so we know exactly where to look when it comes to sourcing the best opportunities. We operate across the UK, and, with over 300 five-star reviews, multiple awards and amazing relationships with the biggest employers in UK Life Science, we give you the best chance of landing your next role.

We have a reputation for recruiting at lightning speed, however, we can only respond to candidates who meet the exact requirements of the position. If you have any queries about a role or application, please visit our website where our amazing candidate support team will be more than happy to help.

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